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DNA双螺旋小沟和大沟的作用各是什么

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DNA双螺旋小沟和大沟的作用各是什么
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分子生物学的吧,
只找到英文的,还挺容易看懂的,您将就着看吧,
In the major and minor grooves, the bases are exposed to solvent and are chemically distinguishable. This means that molecules that interact with particular bases can identify them without disrupting the double helix.
One example is the transcription factor binding. The major and minor grooves provide the structure basis for the protein-DNA interaction.